研究業績

2024年

学術論文

• "Effects of exposure to the neonicotinoid pesticide clothianidin on mouse intestinal microbiota under unpredictable environmental stress."
  Yonoichi S, Hirano T, Hara Y, Ishida Y, Shoda A, Kimura M, Murata M, Mantani Y, Yokoyama T, Ikenaka Y, Hoshi N.
  Toxicol Appl Pharmacol. 482, 116795 (2024).
• "Genes involved in osteogenic differentiation induced by low_intensity pulsed ultrasound in goldfish scales"
  Tabuchi Y, Kuroda K, Furusawa Y, Hirano T, Nagaoka R, Omura M, Hasegawa H, Hirayama J, Suzuki N
  Biomed Rep 22, 2, 18 (2024).
• "Hydroxylated-Benz[a]anthracenes Induce Two Apoptosis-Related Gene Expressions in the Liver of the Nibbler Fish Girella punctata"
  Rafiuddin MA, Matsubara H, Hatano K, Honda M, Toyota K, Kuroda K, Tsunoda K, Furusawa Y, Tabuchi Y, Hirano T, Sakatoku A, Hong CS, Srivastav AK, Amornsakun T, Shimizu N, Zanaty MI, Harumi T, Yamauchi K, M_ller T, Tang N, Hattori A, Hayakawa K, Suzuki N
  Toxics 12, 915 (2024).
• "Genes involved in osteogenic differentiation induced by low_intensity pulsed ultrasound in goldfish scales"
  Tabuchi Y, Kuroda K, Furusawa Y, Hirano T, Nagaoka R, Omura M, Hasegawa H, Hirayama J, Suzuki N
  Biomed Rep 22, 18 (2024).
• "Effects of exposure to the neonicotinoid pesticide clothianidin on mouse intestinal microbiota under unpredictable environmental stress"
  Yonoichi S, Hirano T（＊責任著者）, Hara Y, Ishida Y, Shoda A, Kimura M, Murata M, Mantani Y, Yokoyama T, Ikenaka Y, Hoshi N
  Toxicol Appl Pharmacol 482, 116795 (2024).
• "Effects of exposure to the neonicotinoid pesticide clothianidin on α-defensin secretion and gut microbiota in mice"
  Yonoichi S, Hara Y, Ishida Y, Shoda A, Kimura M, Murata M, Nunobiki S, Ito M, Yoshimoto A, Mantani Y, Yokoyama T, Hirano T, Ikenaka Y, Yokoi Y, Ayabe T, Nakamura K, Hoshi N＊
  J Vet Med Sci 86, 3, 277-284 (2024).
• "Effect of clothianidin exposure at the no-observed-adverse-effect level (NOAEL) in a mouse model of atopic dermatitis"
  Ishida Y, Yonoichi S, Hara Y, Shoda A, Kimura M, Murata M, Ito M, Nunobiki S, Yoshimoto A, Mantani Y, Yokoyama T, Hirano T, Matsuo E, Ikenaka Y, Hoshi N＊
  J Vet Med Sci 86, 3, 333-339 (2024).
• "Quantification of the tissue distribution and accumulation of the neonicotinoid pesticide clothianidin and its metabolites in maternal and fetal mice"
  Hirano T（＊責任著者）, Ohno S, Ikenaka Y, Onaru K, Kubo S, Miyata Y, Maeda M, Mantani Y, Yokoyama T, Nimako C, Yohannes YB, Nakayama SMM, Ishizuka M, Hoshi N
  Toxicol Appl Pharmacol 484, 116847 (2024).
• "Role of brain monoamines in acetamiprid-induced anxiety-like behavior"
  Hirai A, Toda C, Yohannes YB, Collins N, Tamba M, Nomiyama K, Eguchi A, Hoshi N, Hirano T, Nakayama SMM, Ishizuka M, Ikenaka Y＊
  Toxicology 505, 153839 (2024).
• "No-observed-adverse-effect-level (NOAEL) clothianidin, a neonicotinoid pesticide, impairs hippocampal memory and motor learning associated with alteration of gene expression in cerebellum"
  Hara Y, Shoda A, Yonoichi S, Ishida Y, Murata M, Kimura M, Ito M, Nunobiki S, Yoshimoto A, Mantani Y, Yokoyama T, Hirano T, Ikenaka Y, Tabuchi Y, Hoshi N＊
  J Vet Med Sci 86, 3, 340-348 (2024).

学会発表

• "無毒性量（NOAEL）に潜む農薬類による高次脳機能撹乱と発達神経毒性"
  平野哲史
  金沢大学 日本内分泌撹乱物質学会第26回研究発表会；2024 Dec 6；東京 (2024).

  招待講演
• "フィプロニル代謝物が誘導するミクログリアの活性化とニューロンとの相互作用の撹乱機序の解析"
  平野哲史，池中良徳，星　信彦，田渕圭章
  日本内分泌撹乱物質学会第26回研究発表会；2024 Dec 6-7；東京 (2024).
• "Mechanisms of disturbance of microglia-neuron interactions induced by environmental chemical-induced neuroinflammation"
  Hirano T, Hoshi N, Ikenaka Y, Tabuchi Y
  8th International Chemical Hazard Symposium；2024 Oct 24; Sapporo (2024).
• "Epigenomic Toxicity and Transgenerational Effects in Pesticides"
  Hoshi N, Ito M, Nunobiki S, Yoshimoto A, Mantani Y, Yokoyama T, Hirano T, Ikenaka Y
  8th International Chemical Hazard Symposium；2024 Oct 24-25；Sapporo (2024).
• "Developmental neurotoxicity of fetal and neonatal exposure to the phenylpyrazole pesticide fipronil in mice"
  Yoshimoto A, Ito M, Nunobiki S, Mantani Y, Yokoyama T, Hirano T, Ikenaka Y, Hoshi N
  8th International Chemical Hazard Symposium；2024 Oct 24-25；Sapporo (2024).
• "Paternal Clothianidin Exposure Alters Sperm miRNA Profiles in Mice and Affects Behavior in Male Offspring"
  Ito M, Nunobiki S, Yoshimoto A, Mantani Y, Yokoyama T, Hirano T, Ikenaka Y, Hoshi N
  8th International Chemical Hazard Symposium；2024 Oct 24-25；Sapporo (2024).
• "Transgenerational Effects on Maternal Behavior Due to Exposure to a No-observed-adverse-effect-level (NOAEL) dose of Neonicotinoid Pesticide Clothianidin"
  Nunobiki S, Yoshimoto A, Ito M, Mantani Y, Morishita R, Yokoyama T, Hirano T, Ikenaka Y, Hoshi N
  8th International Chemical Hazard Symposium；2024 Oct 24-25；Sapporo (2024).
• "農薬類が哺乳類の中枢神経系に及ぼす未知の神経毒性メカニズムの探索"
  平野哲史
  日本衛生学会若手研究者夏の集い2024；2024 Aug 19；東京 (2024).
• "フィプロニル代謝物が引き起こすミクログリア－ニューロン間相互作用の撹乱メカニズムの解明"
  平野哲史，池中良徳，星　信彦，田渕圭章
  第51回日本毒性学会学術年会；2024 Jul 3-5；福岡 (2024).